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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK4
All Species:
7.88
Human Site:
S548
Identified Species:
15.76
UniProt:
Q96L34
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L34
NP_113605.2
752
82520
S548
P
A
S
P
S
S
H
S
L
A
P
P
S
G
E
Chimpanzee
Pan troglodytes
XP_512745
736
81102
S533
P
A
A
I
I
S
Q
S
A
R
S
G
E
R
R
Rhesus Macaque
Macaca mulatta
XP_001105523
666
73735
A500
D
F
C
G
P
S
P
A
P
L
H
P
K
R
S
Dog
Lupus familis
XP_541564
690
76525
A523
N
G
K
E
N
R
C
A
S
G
R
N
G
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIP4
752
82625
S548
P
A
S
P
S
S
H
S
L
A
P
P
S
G
E
Rat
Rattus norvegicus
Q8VHF0
797
88733
C544
A
A
S
P
A
S
L
C
A
T
S
T
C
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
I536
P
V
A
S
T
H
S
I
S
S
A
A
T
P
D
Chicken
Gallus gallus
Q9IA88
798
88848
P565
M
G
G
A
S
L
L
P
V
S
F
Q
E
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S752
S
A
L
Y
Q
S
P
S
D
S
P
P
P
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
A883
R
S
A
T
T
N
S
A
N
M
G
A
S
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
E346
P
S
G
Y
L
E
S
E
F
Q
E
T
T
D
S
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
V467
Y
K
E
E
D
S
T
V
S
I
L
P
T
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
75.8
88.4
N.A.
97.6
60.4
N.A.
64.4
32.4
N.A.
29.3
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
100
94.4
77.9
89.3
N.A.
98.9
73.5
N.A.
77.3
50
N.A.
41.2
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
26.6
13.3
0
N.A.
100
26.6
N.A.
6.6
13.3
N.A.
33.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
20
13.3
N.A.
100
33.3
N.A.
40
26.6
N.A.
40
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
25
9
9
0
0
25
17
17
9
17
0
0
0
% A
% Cys:
0
0
9
0
0
0
9
9
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
9
0
0
0
0
9
9
% D
% Glu:
0
0
9
17
0
9
0
9
0
0
9
0
17
0
17
% E
% Phe:
0
9
0
0
0
0
0
0
9
0
9
0
0
0
0
% F
% Gly:
0
17
17
9
0
0
0
0
0
9
9
9
9
25
9
% G
% His:
0
0
0
0
0
9
17
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
9
0
9
0
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
9
0
9
9
17
0
17
9
9
0
0
0
17
% L
% Met:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
9
0
0
9
0
0
9
0
0
0
% N
% Pro:
42
0
0
25
9
0
17
9
9
0
25
42
9
17
0
% P
% Gln:
0
0
0
0
9
0
9
0
0
9
0
9
0
0
0
% Q
% Arg:
9
0
0
0
0
9
0
0
0
9
9
0
0
25
17
% R
% Ser:
9
17
25
9
25
59
25
34
25
25
17
0
25
17
25
% S
% Thr:
0
0
0
9
17
0
9
0
0
9
0
17
25
9
0
% T
% Val:
0
9
0
0
0
0
0
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _